References

1 USDHHS. Cancer.A Report of the Surgeon General.
Rockville, MD: Office of Smoking and Health, 1982.
2 Mokdad AH,Marks JS, Stroup DF, Gerberding JL. Ac-
tual causes of death in the United States, 2000 [Spe-
cial Communication]. JAMA 2004; 291(10):1238–45.
3 Centers for Disease Control and Prevention. Tobacco
use among adults—United States, 2005.MMWR 2006;
55:1145–1148.
4 Gonzales D, Rennard SI, NidesMet al. Varenicline, an
a4β2 nicotinic acetylcholine receptor partial agonist,
vs sustained-release bupropion and placebo for smok-
ing cessation: a randomized controlled trial. JAMA
2006; 296:47–55.
5 Hughes JR, Stead LF, Lancaster T. Antidepressants
for smoking cessation; Art. No. CD000031. DOI:
10.1002/14651858.CD000031.pub3, 2004.
6 Jorenby DE, Hays JT, Rigotti NA et al. for Vareni-
cline Phase 3 Study Group. Efficacy of varenicline, an
a4β2 nicotinic acetylcholine receptor partial agonist,
vs placebo or sustained-release bupropion for smok-
ing cessation: a randomized controlled trial. JAMA
2006; 296:56–63.
7 Silagy C, Lancaster T, Stead L, Mant D, Fowler G.
Nicotine replacement therapy for smoking cessation.
Cochrane Database Syst Rev 2004; 3:CD000146.
8 CDC.Annual smoking-attributablemortality, years of
potential life lost, and economic costs—United States,
1995–1999. MMWR 2002; 51:300–3.
9 USDHHS. The Health Consequences of Smoking: A Report
of the Surgeon General. Bethesda, MD: US Department
of Health and Human Services, Centers for Disease
Control and Prevention, National Center for Chronic
disease Prevention and Health Promotion, 2004.
10 Center for Disease Control. Cigarette smoking at-
tributable mortality—United States. MMWR 2003;
52(35):842–4.
11 Gotay C. Behavior and cancer prevention. J Clin Oncol
2005; 23:301–10.
12 Peto R, Lopez AD, ThurnM, Heath C, Doll R.Mortal-
ity from smoking worldwide. BMJ 1996; 52:12–21.
13 Yoder L. Lung cancer epidemiology. Medsurg Nurs
2006; 15(3):171–5.
14 Jemel A, Siegel R,Ward E et al. Cancer statistics 2006.
Cancer J Clin 2006; 56(2):106–30.
15 Spiro SG, Silvestri GA. One hundred years of lung
cancer. Am J Respir Crit Care Med 2005; 172:523–
39.
16 Knop C. Lung Cancer. Boston,MA: Hones and Barlett,
2005.
17 Pastorino U. Early detection of lung cancer. Thematic
Rev Ser 2006; 73:5–13.
18 Thun M, Day-Lally C, Myers D et al. Trends in Tobacco
Smoking and Mortality from Cigarette Use in Cancer Pre-
vention Studies I (1959 through 1965) and II (1982 through
1988). Washington, DC: National Cancer Institute,
1997.
19 Thun MJ, Lally CA, Flannery JT, Calle EE, Flanders
WD, Heath CW, Jr. Cigarette smoking and changes in
the histopathology of lung cancer. J Natl Cancer Inst
1997; 89:1580–6.
20 Wynder E, Muscat JE. The changing epidemiology
of smoking and lung cancer. Environ Health Perspect
1995; 103(Suppl 8):143–8.
21 Stampfer M. New insights from British doctors study.
Br Med J 2004; 328(7455):1507.
22 National Cancer Institute. Cigarette Smoking and Can-
cer. Questions and Answers, 2004 [cited October
12, 2006]. Available from http://www.cancer.gov/
cancertopics/factsheet/Tobacco/cancer.
23 Kamholz SL. Pulmonary and cardiovascular con-
sequences of smoking. Med Clin North Am 2004;
88:1415–30.
24 Peto R, Darby S, Deo H et al. Smoking, smoking ces-
sation, and lung cancer in the UK since 1950: com-
bination of national statistics with two case–control
studies. BMJ 2000; 321(7257):329.
25 Albert A, Samet J. Epidemiology of lung cancer. Chest
2003; 123(Suppl 1):21S–49S.
26 US Public Health Service. Surgeon General’s Advisory
Committee on Smoking and Health.Washington, DC: US
Public Health Service, 1964.
27 American Cancer Society. Cancer Facts and Figures. At-
lanta, GA: American Cancer Society, 2004.
28 Mackay J, Amos A. Women and tobacco. Respirology
2003; 8:123–30.
29 Siegfriend J. Woman and lung cancer: does estrogen
play a role? Lancet Oncol 2001; 2(8):606–13.
30 US Environmental Protection Agency. Respiratory
Health Effects of Passive Smoking: Lung Cancer and Other
Disorders.Washington, DC: US EPA, 1992. Report No.:
Publication EPA/600/6-90/006F.
31 USDHHS. The Health Consequences of Using Smokeless
Tobacco. A Report of the Advisory Committee to the Sur-
geon General. NIH Publication No 86-2874 1986 [cited
May 8, 2006]. Available from http://profiles.nlm.nih.
gov/NN/B/B/F/C/ /nnbbfc.pdf.